Human data

Highly pleiotropic variants of human traits are enriched in genomic regions with strong background selection
We investigate the association between pleiotropy degree and the strength of background selection using data from the GWAS Catalog.
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GWEHS: A Genome-Wide Effect Sizes and Heritability Screener
We develop a tool that process data from the GWAS Catalog and performs analyses on the loci effect size distributions and contributions to heritability. The tool is accessible via an interactive web site (http://gwehs.uvigo.es), and a docker image.
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GWEHS: A Genome-Wide Effect Sizes and Heritability Screener
Inferring the nature of missing heritability in human traits using data from the GWAS Catalog
Using data from the GWAS Catalog, we infer that the loci effect sizes follow a log-normal distribution, and the heritability gap may never be closed for many quantitative traits.
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Inferring the nature of missing heritability in human traits using data from the GWAS Catalog