De novo mutation rate variation and its determinants in Chlamydomonas
A study of comparative mutability between
and its closest known relative
, using WGS data from mutation accumulation lines maintained over nearly 1000 generations.
Inbred lab mice are not isogenic: genetic variation within inbred strains used to infer the mutation rate per nucleotide site
Using WGS data in mouse, we show a novel estimation of mutation rate in inbred lines, based on the observed genetic variation and the expected site frequency spectrum.