Eugenio López-Cortegano
Eugenio López-Cortegano
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Mutation
De novo mutation rate variation and its determinants in Chlamydomonas
A study of comparative mutability between
Chlamydomonas reinhardtii
and its closest known relative
C. incerta
, using WGS data from mutation accumulation lines maintained over nearly 1000 generations.
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Inbred lab mice are not isogenic: genetic variation within inbred strains used to infer the mutation rate per nucleotide site
Using WGS data in mouse, we show a novel estimation of mutation rate in inbred lines, based on the observed genetic variation and the expected site frequency spectrum.
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