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• The rate and spectrum of new mutations in mice inferred by long-read sequencing
• Publications
• An estimate of fitness reduction from mutation accumulation in a mammal allows assessment of the consequences of relaxed selection
• Variation in the spectrum of new mutations among inbred strains of mice
• Rates and spectra of de novo structural mutations in Chlamydomonas reinhardtii
• Prediction of fitness under different breeding designs in conservation programs
• Genetic purging in captive endangered ungulates with extremely low effective population sizes
• purgeR: Inbreeding and purging in pedigreed populations
• Long-term exhaustion of the inbreeding load in Drosophila melanogaster
• Highly pleiotropic variants of human traits are enriched in genomic regions with strong background selection